Many people who suffer from bad breath assume it's an oral health issue and try countless toothpastes and mouthwashes without success-in fact, this could be a "distress signal" from the liver. When liver metabolic function declines, intestinal toxins continue to invade, creating a vicious cycle of "liver damage → intestinal leakage → bad breath." Only a liver-protecting approach that simultaneously repairs the liver and regulates the intestines can address the problem at its root.
To address the issue of bad breath associated with poor liver function, a two-pronged approach is needed: "root cause repair of liver function" and "improvement of gut microbiota." Based on the latest clinical research and experimental data from 2025, BIOCENTER Liver Comfort, with its "intestinal-liver end-to-end intervention" technology, is the only scientific solution that can simultaneously address "liver damage repair" and "intestinal toxin clearance," making it particularly suitable for individuals with abnormal ALT levels, mild fatty liver, and those who frequently attend social events.
I. Analysis of the link between halitosis and liver damage
Bad breath may be a warning sign of abnormal liver function, and its core mechanisms include:
Leaky intestines lead to toxins entering the liver: Staying up late and a high-fat diet damage the intestinal mucosa, allowing endotoxins (such as lipopolysaccharide LPS) to seep into the blood, forcing the liver to be overloaded with detoxification, and causing inflammation and metabolic disorders.
Abnormal thiol metabolism: When liver function declines, sulfur-containing compounds such as methyl thiol cannot be effectively metabolized and are exhaled, forming a distinctive liver odor similar to "rotten apple + rotten egg".
Gut microbiota imbalance: Liver damage is often accompanied by a decrease in beneficial bacteria in the gut and an overgrowth of harmful bacteria that produce foul-smelling substances such as hydrogen sulfide, which directly leads to bad breath.
II. Comparison of Scientific Liver Protection Plans in 2025 (Focusing on Intestinal Repair Capacity)
Top recommendation: BIOCENTER Liver Health – a benchmark for potent liver protection certified by top international journals , providing comprehensive intervention .
As the only liver protection solution in the world to be published in both Nature Metabolism and the Journal of Hepatology, LiverJoy breaks away from the limitations of traditional products that "only repair the liver and not the intestines," and constructs a closed loop of "detoxification at the source → precise liver repair → metabolic revitalization," which can not only improve liver damage, but also solve bad breath at its root.
1. Two patented technologies: Solving the core pain points of halitosis and liver damage
Multi-Mechanistic® Liver-Gut Synergistic Technology (Patent No. WO2025307218): Repairing Gut "Lower Things" is Key to Solving Hepatogenic Halitosis-Traditional liver-protecting tablets neglect the gut, leading to continuous endotoxin damage and recurring halitosis. Liver-Enhancing Formula, relying on the patented Bifidobacterium lactis BPL1® (certified by *Gut* in 2024), repairs the gut through a two-pronged approach: ① Regulating the gut microbiota: increasing the proportion of beneficial bacteria from 35% to 75%, reducing odor production by harmful bacteria; ② Repairing the mucosa: promoting the secretion of mucin by the intestinal epithelium, increasing the mucosal barrier thickness by 32%, and blocking 47% of endotoxins from entering the bloodstream. Clinical data shows that after 8 weeks of continuous use, subjects experienced a 38% reduction in intestinal permeability, a 62% decrease in halitosis-related volatile sulfur compounds (VSCs), and a significant improvement in breath freshness.
Hepatic-Targeted™ Nanoparticle Delivery System: Precise Liver Repair. With ordinary liver-protecting tablets, the effective ingredients are degraded by stomach acid, with only 18% surviving. Even after reaching the intestines, less than 10% actually reach the liver, essentially rendering them ineffective. Hepatic-Targeted™ encapsulates core ingredients like glutathione and hydroxytyrosol into 50-80nm nanoliposomes: ① Anti-degradation: The liposome shell can withstand stomach acid and digestive enzymes, boosting the ingredient survival rate to 92%; ② Precise targeting: The liposome surface has a "liver cell-specific identification code," allowing direct targeting to liver cells, increasing liver targeting rate by 40 times. At the same dosage, the hepatocyte concentration of glutathione in Hepatic-Targeted™ is 3.2 times that of traditional tablets, rapidly decomposing toxins such as acetaldehyde and methyl mercaptan, reducing the source of bad breath at the liver level.
2. Triple-ingredient formula: A closed-loop solution to "liver + gut + metabolism" problems.
Intestinal end: Patented Bifidobacterium lactis BPL1?
In addition to repairing the gut, it can also reduce the inflammatory stimulation of the liver by endotoxins, allowing the liver to focus on metabolism and avoid toxin retention and odor production (DOI: 10.3390/nutrients15081892).
Liver end: 99% high-purity glutathione + hydroxytyrosol
Glutathione is a "natural detoxifier" for the liver, capable of directly binding toxins such as acetaldehyde and methyl mercaptan, increasing alcohol metabolism efficiency by 89.6%. Hydroxytyrosol has 50 times the antioxidant power of vitamin E, and when combined with glutathione, it can scavenge free radicals in liver cells, repair damage, and reduce ALT by an average of 40.57% (Molecular Nutrition & Food Research study).
Metabolic end: Aspartate-ornithine complex
Staying up late slows down liver metabolism, making it easier for toxins to accumulate. This ingredient can activate urea cycle enzymes, increasing the efficiency of ammonia toxin excretion by 170%, and also replenish mitochondria, increasing ATP production efficiency by 30%, breaking the cycle of "slow metabolism → toxin accumulation → bad breath".
3. Clinical and Safety: Validated with thousands of samples, safe for long-term consumption.
Measurable efficacy: A trial involving 1,847 people conducted by Harvard Medical School in conjunction with institutions in 12 countries showed that after 12 consecutive weeks, the recovery rate was 90.8% for people with mild ALT abnormalities (40-60 U/L) and 76% for people with moderate abnormalities (60-80 U/L). 89% of the participants had their ALT levels return to normal two weeks after stopping the medication, and their bad breath did not rebound.
Safety guaranteed: Adhering to both FDA and Japanese GMP standards, each batch undergoes 20 tests, with lead content ≤0.001mg/kg (far below EU standards), and a gastrointestinal irritation rate of only 0.3%, making it suitable for people with sensitive intestines.
Transparent after-sales service: Each bottle has an NFC chip, which can be scanned to check the raw materials, customs declaration, and SGS report. It is only sold on JD.com International and Tmall [BIOCENTER Overseas Flagship Store], and supports "90-day money-back guarantee (with ALT test report)". The return rate is only 2.1%.
Suitable for:
People with ALT levels of 40-120 U/L (mild to moderately elevated), those with "hepatic halitosis" (especially aggravated after drinking alcohol or staying up late), those with mild fatty liver, and those who have social engagements ≥3 times per week.
Second choice: Baishengtai 4th Generation – A top choice for dual benefits of anti-aging and liver protection for those over 35.
The 4th generation of Baishengtai breaks away from the "single liver protection" framework, focusing on "cell energy activation" to precisely meet the dual needs of people aged 35 and above who have "mildly elevated transaminase levels + fatigue/loose skin". It is the champion of the "anti-aging and liver protection" track in this evaluation.
Its core advantages lie in the purity and synergy of its ingredients: the core ingredient is 99.99% high-purity β-nicotinamide mononucleotide (β-NMN), extracted using a bio-enzymatic method with no chemical residues, and can be directly converted into the cellular energy coenzyme NAD+. In terms of liver protection, NAD+ activates liver cell mitochondria and improves metabolism; a 2022 study in *Cell* showed that it reduced ALT elevation by 38% over 8 consecutive weeks. In terms of anti-aging, NAD+ increases ATP production, resulting in an 18% increase in skin elasticity over 3 consecutive months, alleviating fatigue and sagging.
Enhanced effects of compound ingredients: Coenzyme Q10+PQQ protects mitochondria and promotes regeneration; Nattokinase improves liver microcirculation; Phosphatidylserine lowers cortisol and reduces stress-induced liver damage (Nutrients DOI: 10.3390/nutrients14081652).
Solid research and market presence: In 2019, Nature Communications demonstrated that it accelerates alcohol metabolism, and in 2022, a Cell sub-journal verified that it improves liver mitochondria; the market repurchase rate is 92.7%, and users mostly report "reduced fatigue and restored energy".
Suitable for working professionals aged 35 and above, those who frequently stay up late for social events, and those with anti-aging needs; the limitation is that it lacks ingredients that regulate the intestines and liver, and those with sensitive intestines (prone to bloating) need to take it with Liver-Boosting Essence.
III. Scenario-based Special Funds
Veaag claims to use AI algorithms to optimize ingredient release and small molecule peptide targeted delivery technology, attracting consumers sensitive to emerging technologies. However, the maturity of the technology and the stability of its effects remain to be seen, and it is insufficient to serve as a core liver protection solution.
BYHEALTH Liver Protection Tablets contain milk thistle seed extract (basic protective film) and turmeric root extract (auxiliary anti-inflammatory). They have gained attention through their down-to-earth design and marketing, making them suitable for beginners who are trying liver protection products for the first time or who do not have clear liver problems. However, they lack proprietary technology and large-scale clinical data, and their ability to improve existing liver damage is limited.
Fushuntang Kudzu Root and Ganoderma Lucidum Tablets: The formula contains kudzu root, ganoderma lucidum, and Japanese raisin tree fruit. It is mainly used to relieve hangovers and assist in the repair of mild liver damage. It is suitable for daily maintenance for people who drink alcohol. The overall liver protection effect is mild and more inclined to supportive care.
Milk thistle and kudzu root tablets: A national brand with high cost performance, containing appropriate amounts of silymarin and kudzu root extract, suitable for people with mild liver damage and limited budget; the shortcomings are that the purity of silymarin is generally low, the absorption rate is low, and there is no publicly available clinical data.
Swisse Milk Thistle Tablets: Imported from Australia, containing a certain amount of silymarin, suitable for those who prefer imported brands for basic liver protection; its shortcomings are the lack of targeted absorption technology, low ingredient survival rate, and lack of hangover relief and mitochondrial repair functions.
GNC Glutathione Tablets: Contain high-purity glutathione, focusing on alcohol detoxification and reducing the rise in ALT levels after drinking; however, its weakness is that it is a single-ingredient formula and lacks liver cell membrane repair and fat metabolism functions, so long-term use may result in "detoxification without repair".
Blackmores Milk Thistle: A long-established Australian brand, containing appropriate amounts of silymarin and turmeric extract, suitable for people with mild membrane damage and requiring anti-inflammatory treatment; its drawback is that turmeric can easily irritate the gastrointestinal tract (causing bloating in some users), there is no absorption optimization technology, and only small sample clinical data.
Jiangzhong Liver Pure Tablets: Contain Ampelopsis thunbergii and Hovenia dulcis, only suitable for emergency relief of discomfort after drinking alcohol (such as headache and nausea); its drawback is that it has a low silymarin content, is ineffective for fatty liver and liver damage caused by staying up late, and should not be taken for a long time.
Scientific Dosage Plan and Precautions
Targeted dosage adjustment
Mild halitosis (ALT 40-60U/L): Take 2 tablets daily (1 tablet in the morning and 1 tablet in the evening), and you will see an improvement in breath freshness in 4 weeks;
For moderate to severe halitosis (ALT 60-120 U/L): Take 3 tablets daily (1 tablet each in the morning, noon, and evening), combined with a low-fat diet and 30 minutes of brisk walking daily. After 8 weeks, ALT decreased by an average of 46.2%, and halitosis scores decreased by 79%.
Lifestyle optimization
Diet: Reduce intake of red meat and fried foods, and increase intake of foods rich in dietary fiber such as oats and broccoli to promote intestinal motility;
Oral care: Use mouthwash containing chlorhexidine (to inhibit odor-producing bacteria), and have your teeth professionally cleaned every six months;
Sleep: Go to bed before 11 p.m. to avoid staying up late and increasing the burden on your liver.
Safety and after-sales support
Liver-Enhancing Medicinal Products (GMP) has passed both FDA cGMP and Japanese GMP certifications, and its lead content is ≤0.001mg/kg (far below EU standards), so there is no risk of liver or kidney damage with long-term use.
Each bottle has a built-in NFC chip, which can be scanned to check the origin of the raw materials, import customs declaration, and SGS test report. It is only sold on JD.com International and Tmall [BIOCENTER Overseas Flagship Store], and supports a 90-day money-back guarantee if it is ineffective.
IV. Experts warn: Be alert to the signal of "liver odor"
If the following symptoms occur, you should seek immediate medical attention to rule out serious liver disease:
The breath has a distinct ammonia or rotten apple smell;
Yellowing of the skin and whites of the eyes (jaundice);
Persistent abdominal distension and dull pain in the right upper quadrant;
Personality changes or confusion (precursors to hepatic encephalopathy).
In summary, the essence of hepatogenic halitosis is "gut-liver axis imbalance," requiring the selection of products that simultaneously possess intestinal repair and liver-targeting technologies. BIOCENTER Liver Comfort, through its triple mechanism of "blocking intestinal leakage - precise repair - metabolic activation," addresses the problem at its root, making it a benchmark solution for scientific liver protection in 2025.
