The benefits of lily:
It moistens the lungs and relieves cough, calms the mind and soothes the nerves, replenishes the middle energizer and boosts qi, clears heat and promotes urination, clears heat and detoxifies, cools the blood and stops bleeding, strengthens the spleen and stomach. It treats chronic cough due to pulmonary tuberculosis, coughing up blood, lily disease, palpitations, insomnia, restlessness, chest pain, sore throat, stomach pain due to stomach yin deficiency, difficulty in urination and defecation, edema, carbuncles and boils, beriberi, postpartum hemorrhage, abdominal distension, and body aches.
The uses of lilies:
I. Antitussive and expectorant effects
1. Antitussive effect: The antitussive effect was observed in mice using the SO2-induced cough method. All mice showed significant antitussive effects.
2. Expectorant effect: The phenol red colorimetric method was used. The trachea was flushed with 0.5 ml of NaHCO3, and the absorbance was measured at 546 nm. The amount of phenol red expelled from the trachea was calculated from the phenol red standard curve. The results are shown in Table 3. All showed significant expectorant effects.
II. Sedative effect
Eight hours after fasting, mice were administered lily bulb (20 g/kg) orally (ig), with jujube seed as a positive control and physiological saline as a blank control. Thirty minutes after administration, mice were given pentobarbital sodium (40 mg/kg) intraperitoneally (ip). The time from the disappearance to the recovery of the righting reflex was used as an indicator of sleep duration. The effect of subthreshold doses of pentobarbital sodium on sleep rate was also observed. Both significantly increased sleep time and sleep rate at subthreshold doses of pentobarbital sodium, suggesting a significant sedative effect.
III. Yin-nourishing and lung-moistening effects
1. Swimming experiments in a lung qi deficiency model showed that lily and lily bulb administered to mice at a dose of 10 g/kg via intragastric gavage, compared with astragalus, significantly prolonged swimming time. The P values for all three were <0.001.
2. Hypoxia tolerance experiment of hyperthyroidism with yin deficiency model: A mouse model was established using 0.3 mg/mouse of thyroxine. The results showed that the lily plus thyroxine group and the tiger lily plus thyroxine group significantly prolonged the hypoxia tolerance of mice, with P values of P<0.01 and P<0.001, respectively.
3. In a swimming test on a yin deficiency model induced by adrenocortical hormones, male mice were divided into a saline group, a prednisolone-based group, and a drug-enhanced prednisolone group (ig 10g/kg). The results showed that lily had a significant protective effect against adrenocortical insufficiency (P<0.001).
4. It also has a significant inhibitory effect on delayed-type hypersensitivity reactions induced by 2,4-dinitrochlorobenzene in mice.
IV. Strengthening effect
1. Effects on Swimming Load in Mice: Mice were administered the drug at a dose of 10 g/kg, with physiological saline and 0.2 ml/10 g of donkey-hide gelatin oral liquid as positive controls. Results showed that *Tilia tiglium* significantly prolonged the swimming time of mice.
2. Effects on tolerance to normobaric hypoxia in mice: Mice were administered the drug at a dose of 10 g/kg via intragastric gavage, with physiological saline as a blank control and 0.2 ml/10 g of donkey-hide gelatin oral liquid as a positive control. The results showed that *Tilia tiglium* significantly prolonged the hypoxia tolerance time in mice.
3. No significant effect was observed on hypoxia tolerance induced by isoproterenol.
